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AMINO ACID CHLOROMETHYL KETONES
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DeCS
Descriptor
English
:
Amino Acid Chloromethyl Ketones
Descriptor
Spanish
:
Clorometilcetonas de Aminoácidos
Descriptor
Portuguese
:
Clorometilcetonas de Aminoácidos
Synonyms
English
:
Chloromethyl Ketones, Peptide
Ketones, Peptide Chloromethyl
Peptide Chloromethyl Ketones
Tree Number:
D12.125.065
Definition
English
:
Inhibitors of
SERINE ENDOPEPTIDASES
and sulfhydryl group-containing
enzymes
. They act as
alkylating agents
and are known to interfere in the translation process.
Pharmacological Action:
Alkylating Agents
Protein Synthesis Inhibitors
Serine Proteinase Inhibitors
History Note
English
:
77
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
594
Unique Identifier:
D000590
Occurrence in VHL
:
Similar:
DeCS